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Dublin, Feb. 11, 2025 (GLOBE NEWSWIRE) — The “Ocular Melanoma – Epidemiology Forecast – 2034” report has been added to ResearchAndMarkets.com’s offering.

The report delivers an in-depth understanding of ocular melanoma, historical and forecasted epidemiology in the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan.

The Ocular Melanoma epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by diagnosed incident cases, type-specific cases, mutation-specific cases, age-specific cases, stage-specific and treated cases in the United States, EU4 countries (Germany, France, Italy, Spain) and the United Kingdom, and Japan from 2020 to 2034.

Ocular Melanoma Epidemiology

• Among the 7MM, the United States accounted for the highest number of diagnosed incident cases of ocular melanoma, which is 49.0% of the diagnosed incident cases of ocular melanoma in 2023.

• In the US, out of all diagnosed incident cases of uveal melanoma, choroidal cases were highest, followed by ciliary body and iris melanoma in 2023.

• Among the EU4 and the UK, the United Kingdom accounted for the highest number of ocular melanoma cases, followed by France, whereas Spain accounted for the lowest number of diagnosed incident cases of ocular melanoma.

• In Japan, the highest mutation type-specific cases of ocular melanoma were for GNA11, followed by GNAQ, BAP1, and SF3B1 mutation in 2023.

Key Highlights

• Ocular melanoma, while rare, is the most common primary cancer of the eye in adults, primarily affecting the uveal tract. The condition originates from melanocytes, pigment-producing cells, and can potentially metastasize, commonly to the liver.

• Ocular melanoma can be divided into uveal and non-uveal melanoma. Uveal melanoma comprises the larger group of ocular melanoma and consists of choroidal, ciliary body, and iris melanoma. Non-uveal melanoma includes conjunctival melanoma and ocular melanoma from other sites.

• Ocular melanoma predominantly affects older individuals, with a higher incidence in fair-skinned individuals and those with lighter eye colors. Risk factors include dysplastic nevus syndrome, certain cutaneous nevi, and a family history of systemic and ocular cancers, possibly linked to genetic mutations like BAP1, GNAQ, and GNA11 alterations.

• Ocular melanoma may manifest with varied symptoms, including blurred vision, photopsia, and metamorphopsia, or remain asymptomatic for years. Diagnosis involves a comprehensive clinical evaluation, specialized tests like ocular ultrasound, fluorescein angiography, optical coherence tomography, and, in some cases, fine needle aspiration biopsy for genetic analysis.

• In 2023, the United States accounted for the highest number of diagnosed incident cases of ocular melanoma in the 7MM.

• In the United States, ocular melanoma primarily affects individuals aged 40-70 years, constituting approximately ~60% of the total cases.

• Among the EU4 and the UK, out of all diagnosed incident cases of uveal melanoma, choroidal cases were highest, followed by ciliary body and iris melanoma in 2023.

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